We can never manage uncertainty. Yet in today’s business environment we confront it all the time. This talk explains why Agile principles are needed to make good management decisions in an uncertain business environment and why past practices no longer work. We will review what drives business uncertainty and why its here to stay. We will introduce Agile management principles and explain how they help us navigate uncertainty. We will learn how to use these principles to exploit new business opportunities, reduce business risk and increase returns, while decreasing investment requirements.